RADICAL RESECTION OF LOCALLY ADVANCED CHEST WALL CSCC WITH MUSCLE FLAP RECONSTRUCTION

Sunday, February 12, 2023

7:00am – 8:00am East Coast USA Time

Presenter(s)

Matthew Dietz, BS

Medical Student
West Virginia School of Osteopathic Medicine, United States

Principal Contact(s)

MC

Mark Choueiri, MD

General Surgery Physician
West Virginia University, Charleston, United States

Objectives: Outcomes in those with high-risk Cutaneous Squamous Cell Carcinoma (cSCC) are poor. Upon incidence of metastasis, the mortality rate has been shown to be >70%. Currently, there are no standardized therapy recommendations to manage patients of this severity. Cisplatin as monotherapy or combination with Fluorouracil (5-FU), and radiotherapy followed by surgical intervention are the most likely regimens used in the treatment of metastatic cSCC. Secondary chemotherapy options include Carboplatin and Paclitaxel. In this case, we report the effectiveness of palliative chemoradiotherapy (CRT) using Carboplatin and Paclitaxel agents with Intensity Modulated Radiation Therapy (IMRT) followed by radical surgical resection, and later, muscle flap reconstruction to treat a Stage IV cSCC of the trunk.

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